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Stenotrophomonas maltophilia ( S. maltophilia) is a free living, motile, aerobic, oxidase negative, glucose non-fermentative Gram-negative bacillus (GNB). Stenotrophomonas maltophilia is a globally emerging pathogen that causes serious infectious complications in immunocompromised patients in particular. Stenotrophomonas maltophilia is a Gram-negative bacillus found as a free-living organism in most aquatic and humid environments including hospital drinking water, and often associated with . It also exhibits a wide range of drug resistance mechanisms and this complicates the management of infections caused by this GNB. Stenotrophomonas maltophilia is a common nosocomial organism but an uncommon cause of infective endocarditis. S. maltophilia has gained importance as a hospital pathogen because of Complications of severe COVID-19 pneumonia are common. S. maltophilia positive patients with dysglycemia had more pulmonary exacerbation events compared to NGTs (1.22 vs 0.63, P=0.003). If this occurs the immune system could confuse an immune attack against the bacteria stenotrophomonas with nerve endings. Stenotrophomonas maltophilia is a well-known opportunistic Gram-negative bacterium causing mainly hospital-acquired infections, which rarely affects the musculoskeletal system.We report the first case, to our knowledge, of a periprosthetic infection caused by this pathogen in an artificial joint. S. maltophilia is the only species of the genus Stenotrophomonas known to infect humans. Stenotrophomonas maltophilia may complicate the treatment of diabetic foot infections as an opportunistic pathogen. We report a case of S. maltophilia endocarditis of the native aortic valve. Stenotrophomonas maltophilia is a gram-negative, multidrug-resistant organism that is typically hospital-acquired and associated with high morbidity and mortality [1, 2].It is a free-living organism present in most aquatic and humid environments. Background: Stenotrophomonas (Xanthomonas) maltophilia has been increasingly reported as a nosocomial opportunistic pathogen, responsible for serious infectious complications in immunocompromised patients. The causative pathogen was identified as Stenotrophomonas maltophilia by shotgun metagenomic sequencing of spinal cord aspirate after more than one month of unsuccessful empirical treatment with 6 . Twenty-nine of these 68 patients developed pneumonia, with S. maltophilia being implicated in 10 cases. The microbiology records of a … Stenotrophomonas maltophilia (S. maltophilia) is a widely spread gram negative opportunistic bacterial pathogen with increasing prevalence [9,8,10]. Stenotrophomonas maltophilia is a non-fermentative, Gram-negative bacillus that is ubiquitous in the natural and hospital environment, 1, 2, 3, 4 and exhibits . S. maltophiliais the only species of the genus Stenotrophomonasknown to infect humans. This community is sponsored by the American Lung Association, an Inspire trusted partner. CASE REPORT A 70-year-old woman with several co-morbidities presented reporting hypoglycemia and dyspnea. It is considered an opportunistic pathogen of nosocomial origin most of the time, targeting a specific patients' population. Although generally regarded as an organism of low virulence, S. maltophilia is an emerging multi-drug resistant opportunistic pathogen in hospital and community settings, especially among immunocompromised hosts. All 68 strains of S. maltophilia were resistant to imipenem. At present very limited information is available concerning its clinical significance in the setting of HIV infection. Stenotrophomonas maltophilia (S. maltophilia) is a nosocomial pathogen and a rare cause of infective endocarditis (IE). septic shock, respiratory failure, tissue necrosis and septic thrombophlebitis [3]. The increase in S. maltophilia nosocomial infections is due to the changing nature of the hospital patient population and changes in antibiotic usage . Stenotrophomonas produce butyrolactones which converts to GHB in the human body. Stenotrophomonas maltophilia - Infectious Disease and Antimicrobial Agents Stenotrophomonas maltophilia Microbiology Stenotrophomonas maltophilia is a motile non-fermentative, gram negative bacillus that is readily isolated from environmental sources and water. Stenotrophomonas maltophilia: 1: 1: Anaerobic bacteria . Understanding the implication of long-term broad-spectrum antibiotic treatment in the diabetic patient is important in managing postoperative complications and determining the correct course of treatment. Stenotrophomonas maltophilia is an aerobic, glucose non-fermenting, Gram-negative bacillus that is ubiquitous in water environments. Complications. 1 the reported incidence of s. maltophilia infection … Objectives Stenotrophomonas maltophilia, a Gram-negative non-fermentative bacillus, has emerged as an important nosocomial pathogen in recent years. In a hospital setting, hospitals and clinics), water-based environments, soil, and on contaminated medical devices and solutions. In the immunocompromised host, increasing prevalence and severity of illness is observed, particularly opportunistic bloodstream infections and pneumonia syndromes. Stenotrophomonas maltophilia: a serious and rare complication in patients suffering from burns Stenotrophomonas maltophilia is rarely implicated in clinical infections but it constitutes a significant nosocomial pathogen, especially in immunocompromised patients. Stenotrophomonas maltophilia (S. maltophilia)isan aerobic, nonfermentative, Gram-negative bacterium. Stenotrophomonas maltophilia, a very uncommon pathogen. Stenotrophomonas maltophilia may complicate the treatment of diabetic foot infections as an opportunistic pathogen. Stenotrophomonas maltophilia is a ubiquitous organism associated with opportunistic infections. promised hosts resulting in complications, e.g. Due to low virulence it does not fit in the common definitions of multidrug-resistant organisms (MDRO). [14] Stenotrophomonas maltophilia is an environmental bacterium of growing concern due to its multidrug resistance and pathogenic potential. Risk factors for urinary colonization by this organism include hospitalization, urinary catheterization, and administration of inactive antibiotics. At present very limited information is available concerning its clinical significance in the setting of HIV infection. Stenotrophomonas maltophiliais a gram-negative, opportunistic infection that is usually hospital-acquired and associated with high morbidity and mortality. Stenotrophomonas maltophilia (SM) is a gram-negative bacillus that is increasingly associated with serious nosocomial infections, especially in . Multidrug resistance of the opportunistic pathogen Stenotrophomonas maltophilia is an increasing problem. Though not particularly virulent, S maltophilia has proven itself a formidable pathogen in the setting of intensive healthcare contact, immunosuppression, and other . Stenotrophomonas maltophilia is a Gram-negative, biofilm-forming bacterium. It is ubiquitous in aqueous environments, soil, and plants. However, it has an intrinsic resistance against e.g. Introduction. S. maltophilia. Although fever developed they can cause serious local wound complications in contrast to the common crotaline snakebites (i.e., T. s. stejnegeri and P. mucrosquamatus), thus, requiring repetitive debridement and reconstructive surgeries to restore limb function. Stenotrophomonas maltophilia is an emerging multidrug-resistant global opportunistic pathogen. It is an obligate aerobe, and is capable of growth between 5o and 40oC ( 18 ). is a species of gram-negative, nonfermentive bacteria that is not generally pathogenic to healthy humans (2). A 61-year-old male presented with persistent productive cough for 5 months that was not . This organism should be considered as a potential cause of . Methods Stenotrophomonas maltophilia: Changing Spectrum of a Serious Bacteral Pathogen in Patients wit Cancer Amar Safdar and Kenneth V. Rolston The M. D. Anderson Cancer Center, University of Texas, Houston Stenotrophomonas maltophilia colonization/infection in patients with cancer has significantly increased over the past 2 decades. [13][4][9] It is the only species among the seventeen of the Stenotrophomonas genus that infects man. The Living with Lung Disease Support Community connects patients, families, friends and caregivers for support and inspiration. We describe a case of a previously healthy full-term neonate who was found to have <i>S. maltophilia</i> meningitis and was . Neutropenia is also seen which last more than 10 days. carbapenems [8,9]. Although an uncommon pathogen in. S. maltophilia is gen- The organism has a long history of changing nomenclatures and a complicated phylogeny [247-249]. We report a case of S. maltophilia meningitis in a preterm baby boy after a neurosurgical procedure, successfully treated with trimethoprim-sulfamethoxazole and ciprofloxacin. It is not considered part of normal human flora. Stenotrophomonas (Xanthomonas) maltophilia is an aerobic, non-fermentative, Gram-negative bacillus closely related to the Pseudomonas species, and is widespread in the environment. All patients presented with fever. Latamoxef was effective against 98 . Stenotrophomonas maltophilia is highly resistant to antibiotics. Stenotrophomonas (Xanthomonas) maltophilia has been increasingly reported as a nosocomial opportunistic pathogen, responsible for serious infectious complications in immunocompromised patients. stenotrophomonas maltophilia is an opportunistic, and frequently multidrug-resistant gram-negative bacteria of increasing clinical significance, coinciding with an increased use of mechanical ventilation, indwelling central venous catheters and the widespread use of broad-spectrum antibiotics. Introduction: Stenotrophomonas maltophilia, which is able to form a biofilm, has mostly been related to catheters when it is the agent in hospital infections; these infections generally present as bacteremia and pneumonia, which may progress with complications and result in death. Twenty-three (17 male) cases of S. maltophilia endocarditis were identified. It is frequently isolated from water, soil, animals, plants, and hospital equipment ( 1 - 5 ). Background: Stenotrophomonas (Xanthomonas) maltophilia has been increasingly reported as a nosocomial opportunistic pathogen, responsible for serious infectious complications in immunocompromised patients. Key words: Stenotrophomonas maltophilia,endocarditis,prostheticvalve (Inter Med 49: 1775-1777, 2010) (DOI: 10.2169/internalmedicine.49.3701) Introduction Stenotrophomonas maltophilia (S. maltophilia) is a non-fermentative, Gram-negative, aerobic bacillus that is widely distributed in the natural environment. Stenotrophomonas maltophilia, an intrinsically multidrug resistant gram negative pathogen, is widely distributed in aqueous habitats such as, sink drains, endoscopes and . 543 Case series of Stenotrophomonas Maltophilia as a rare cause of PD Peritonitis Dr Lauren Floyd1, Dr Arvind Ponnusamy1 1Royal Preston Hospital, Preston, United Kingdom Introduction Peritoneal Dialysis (PD) peritonitis is a common and serious cause of PD related complications. In the present case, this organism was either acquired from the hospital (likely source being the ascitic drain) or from the community. We have reviewed other cases of S. maltophilia endocarditis, associated complications, and treatment options. Stenotrophomonas maltophilia is the third cause of nosocomial infections caused by nonfermented gram-negative bacilli.S. The majority of these 10 patients showed lobular infiltration on chest X-ray. Prompt identification of risk factors, particularly the use of medical devices, is necessary for the timely . In this article, the classification and microbiology are outlined, together with clinical presentation, outcomes and management of . Stenotrophomonas maltophilia endocarditis is a rare disease. Stenotrophomonas maltophilia is a Gram-negative aerobic bacillus widely distributed in natural and human environments and has become increasingly responsible for nosocomial infections such as bacteremia, pneumonia, urinary tract infections, skin and soft tissue infections, ocular infections and meningitis [].It is generally considered as an opportunist pathogen with potential risk factors . To date, only 3 cases of osteomyelitis due to this pathogen have been previously referenced. Stenotrophomonas maltophilia outbreaks can occur in hospitals and critical care units. S. maltophilia is an unusual cause of biliary sepsis. At present very limited information is available Stenotrophomonas maltophilia. Stenotrophomonas maltophilia. Recipients of hematopoietic stem complications.2 Some patients require surgery irrespective of the longer duration of antimicrobial [1] Stenotrophomonas maltophilia. Stenotrophomonas maltophilia, particularly in immunocompromised patients, has been implicated as the causative pathogen in respiratory tract infections, endocarditis, bacteremia, meningitis and urinary tract infections. Stenotrophomonas maltophilia previously known as (Xanthomonas) maltophilia is an aerobic gram-negative bacillus that is found in various aquatic environments. Stenotrophomonas maltophilia is a gram-negative rod rarely associated with osteomyelitis. Stenotrophomonas maltophilia, a non-fermenting gram-negative rod, is the third most common after Pseudomonas aeruginosaand Acinetobacter and similar to Achromobacter xylosoxidansand Burkholderia cepacia. Patients and methods: A retrospective survey of clinical and . It general, S. maltophilia BACKGROUND: Stenotrophomonas (Xanthomonas) maltophilia has been increasingly reported as a nosocomial opportunistic pathogen, responsible for serious infectious complications in immunocompromised patients. S. maltophilia is known to cause infection via invasive medical devices such as central venous catheters, 5 chronic indwelling urinary catheters, endotracheal or tracheostomy tubes, 6 and peritoneal catheters, 2 by which the organism bypasses normal host defenses and causes nosocomial outbreaks of infection. There should be a high index of suspicion and low threshold for evaluation for secondary bacterial pneumonia and bacteraemia when a patient is clinically worsening. The bacteria are consistently being implicated in necrotizing otitis, cutaneous infections including soft tissue infection and keratitis, endocarditis, meningitis, acute respiratory . Stenotrophomonas maltophilia (SM) is one of the most common emerging gram - negative micro-organisms found in the sputum colture of people with cystic fibrosis and its prevalence is increasing (Hatziagorou E, 2019).One relevant problem is that SM is a bacteria which is resistant to several antibiotics. Conclusions: Stenotrophomonas maltophilia urinary tract infection is usually associated with a severe clinical course. It is frequently isolated from water, soil, animals, plants, and hospital equipment (1-5). Levofloxacin resolves Stenotrophomonas maltophilia pneumonia. Stenotrophomonas maltophilia is one such organism that has emerged as a multidrug-resistant opportunistic infection of global magnitude. Introduction. Although the organism presents a limited invasiveness, it is emerging as a nosocomial, opportunistic pathogen in immunocompromised hosts [].Approximately 20 cases of S. maltophilia infectious complications have been . It is often seen as a co-organism along with Pseudomonas aeruginosa. maltophilia is the most important genus of Stenotrophomonas that belongs to group V of the Pseudomonas family (16S rRNA based) [, , ].This bacterium is colonized in toilets, water coolers, medical equipment, respiratory tract patients, intravascular catheters . An immune attack at nerve endings could be the cause of fibromyalgia. Of note, pulmonary diseases and thoracic complications were significantly associated with S maltophilia pneumonia, with pulmonary haemorrhage representing a significant independent risk factor for acquired S maltophilia infection (odds ratio [OR] = 3.2; P = .03). It causes a high rate of failure in treatment which results even in deaths. Stenotrophomonas maltophilia is an aerobic, glucose non-fermenting, Gram-negative bacillus that is ubiquitous in water environments. Brain abscesses pose a challenge in diagnosis and treatment, because microbiological diagnosis is not always achieved, antibiotic drugs may not penetrate well into the CNS and some bacteria have resistances to typical empirical .

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